BRAVECTO® injectable
Introducing the first year-long systemic flea and tick protection for dogs — BRAVECTO® injectable
Experience a new unique formulation of fluralaner:
- 12 months of non-stop protection
- Revolutionary crystal injectable formulation of fluralaner
- Vet exclusive
Putting administration back in the hands of the vets to ensure compliance and deliver convenience throughout the year
*Bravecto 150 mg/ml powder and solvent for suspension for injection for dogs will be referenced throughout this website as BRAVECTO injectable
The first-ever year-long systemic flea and tick protection for dogs
A revolutionary injectable with a trusted ingredient: fluralaner
Available exclusively through vets
A Vet-Exclusive Formula
Designed to be the ultimate support for you and your efforts to control parasite infestations and vector-borne diseases.
Certainty
Administering the injection in practice ensures no gaps in year-long protection, eliminating reliance on pet owners to administer products correctly, at the proper frequency.
Convenience
BRAVECTO Injectable is administered as a single injection during a vet visit to provide year-round protection.
Comfort
The innovative suspension of fluralaner crystals allows for simple administration and a favorable pet and owner experience.
Keep Patients Protected for a Full Year
BRAVECTO Injectable
protects dogs 6 months of age or older against multiple species of fleas and tick, including:
Ctenocephalides felis
Ctenocephalides canis
Ixodes ricinus
Ixodes hexagonus
Dermacentor reticulatus
Rhipicephalus sanguineus
Pharmacokinetics
Flea efficacy
Tick efficacy
Pharmacokinetics
Plasma fluralaner concentrations following a single subcutaneous administration1

Efficacy
• Reaches maximum plasma concentrations in approximately 37 days
• Innovative formulation of slowly dissolving crystals results in half-life of approximately 130 days
• Provides sustained efficacy for 12 months following injection
Immediate And Persistent Flea Killing Activity For 12 Months
Duration of efficacy against C felis – adulticide2,a,b

Efficacy
• Achieves efficacy after initial infestations shortly after injection
• Remains efficacious against repeated infestations for a full year
Newly-infested fleas are killed within 24 hours from one week to 12 months after treatment.2,3
aFlea counts are arithmetic means.
bPercent effectiveness is based on arithmetic means.
Newly Emerged Fleas Are Killed Before Viable Eggs Are Produced
Efficacy against C felis – egg production.2,a

Efficacy
• Achieves efficacy quickly after injection
• Remains efficacious for a year
Summary: The flea life cycle is broken due to the rapid onset of action and long-lasting efficacy against adult fleas on the animal and the absence of viable egg production.3
a Flea egg counts are arithmetic means.
Persistent Tick Killing Activity For 12 Months
Duration of efficacy against Rhipicephalus sanguineus (R sanguineus)4

Persistent R sanguineus tick-killing activity from Day 4 after treatment for 12 months. Newly-infested R sanguineus ticks are killed.3,4
a Tick counts are arithmetic means.
Persistent Tick Killing Activity For 12 Months
Duration of efficacy against Dermacentor reticulatus (D reticulatus)5

Efficacy
• Fluralaner kills ticks, reducing the risk of infection with Babesia Canis
• Persistent D reticulatus killing activity from Day 3
• Newly-infested D reticulatus ticks are killed3,5
a Tick counts are arithmetic means.
Persistent Tick Killing Activity For 12 Months
Duration of efficacy against I ricinus 6,7

Efficacy
• Persistent I ricinus killing activity from Day 3
• Newly-infested I ricinus ticks are killed3,6,7
a Flea counts are arithmetic means.
b Percent effectiveness is based on arithmetic means.
Precise Dosing
a BRAVECTO chewable tablets for dogs are indicated for immediate and persistent tick-killing activity for R sanguineus for 8 weeks.
Multi-dose vial allows you to draw the exact dose you need for dogs of any size (15 mg fluralaner/kg body weight; 1 ml/10 kg body weight).
3-year shelf life of BRAVECTO injectable, 3 months at room temperature after reconstitution.
For puppies less than 6 months of age, use BRAVECTO Chew or spot-on with a 12-week duration of efficacy against fleas and ticks*
How To Administer Bravecto
To ensure correct product preparation, follow the step-by-step mixing instructions carefully.
See How Bravecto Is Injected
Here is a video of BRAVECTO Injectable being administered to pets across the UK
What vets involved in clinical field studies say about Bravecto INJECTABLE
“As a practice owner, I have been very engaged with Bravecto Injectable right from the start. The time-saving element for the practice is a significant advantage. I have 815 dogs on my Health Care Plan (HCP) and plan to move them all over at the time of their vaccine. This alignment reduces footfall, phone calls for the team and flea and tick consultations. So far, I have had 100% uptake from clients. It’s all in the delivery and how I tell the clients: ‘I have some good news for you. You know the chew you have to give every 12 weeks for fleas and ticks? Well, I can now give the same thing as an injection while you are here, and it lasts a whole year!’ Clients are over the moon, and every single one has moved over.
So far, I have used over 33 bottles of Bravecto injectable with no adverse events or dogs reacting badly to the 18-gauge needle. This approach also encourage sign-ups to the health care plan and my team is already engaged and fully onboard with this new product and process. With around 3000 clients, 80% of whom are dog owners, I plan to continue using Bravecto injectable to support my clients and their pets.”
Neil Murdoch, BVMS MRCVS
Metro Vets
United Kingdom
It is a highly effective product, and to date, we had nothing on the market offering good antiparasitic (flea and tick) protection for a year.
Translated form original language “original quotation”
Oscar Cortadellas, DVM PhD, Acred. AVEPA Internal Medicine
Clínica Veterinaria Germanias
Gandía, España
Addressing A Pet Owner’s Questions About Bravecto Injectable
Pet owners may have questions. Download our guide containing answers to the most commonly asked questions by pet owners who are considering using BRAVECTO injectable.

Frequently Asked Questions
Why is the product only indicated for dogs from 6 months of age?
Due to the possibility of fast-growing puppies outgrowing the dose over the 12-month duration, the product was developed for dogs and puppies 6 months of age and older.
Can the product be administered at the same time as vaccines?
There is no contraindication to concurrent vaccination. Vets should keep in mind vaccinations may cause fever, lethargy, and inappetence, occurring within the first few days following vaccination.
When should dogs be treated with BRAVECTO Injectable?
Because the efficacy is sustained for an entire year following administration, dogs can be treated whenever they are unprotected against fleas and ticks. Dogs will not require another dose of flea and tick treatment for 12 months for the indicated parasites.
What safety studies have been performed?
A margin of safety study was performed and demonstrated safety at doses of 1X (15 mg/kg), 3X (45 mg/kg) and 5X (75 mg/kg) administered every 4 months for a total of 6 doses. The only treatment-related finding was limited to injection site swellings that resolved over time.
Why is an 18 G needle required for administration?
The formulation is a suspension containing fluralaner powder and an 18-G needle is required to ensure the solid particles in suspension are accurately transferred from the vial into the syringe and from the syringe into the patient.
How much volume is given per dog?
Dogs should be dosed 0.1 ml per kg of body weight. Dogs weighing 10 kg should be injected with 1.0 ml; dogs weighing 15 kg should be injected with 1.5 ml, etc.
When should a dog be re-dosed following initial administration?
To maintain the efficacy of BRAVECTO injectable dogs should be re-dosed 12 months* after the previous injection.
Why is one vial dark in color and the other is colourless?
The sterilization process used for the powder causes the lass to darken in colour, which is not the case for the process used to sterilize the liquid vehicle.
How soon must the product be used after it is mixed, and how must it be stored?
After reconstitution, the suspension must be discarded 3 months from the date of reconstitution. Write the discard date on the label of the glass vial.
If the suspension is left to stand for more than 5 minutes, then it should be shaken thoroughly for at least 30 seconds to resuspend the product before administration.
This product does not require any special temperature storage conditions. After reconstitution, store below 30°C.
Request further information from the MSD team on how to introduce Bravecto injectable in your practice
We’ll answer your questions to help ensure you’re ready to prescribe BRAVECTO injectable and launch this product in style.
„*“ Mit * gekennzeichnete Felder sind Pflichtfelder
Discover our whole Bravecto family

References
- BRAVECTO Chew Datasheet. NOAH Compendium [online]. Accessed August 1, 2025. https://www.noahcompendium.co.uk/?id=-454352&fromsearch=true#iosfirsthighlight
- Fisara P, Guerino F. Year-round efficacy of a single treatment of fluralaner injectable suspension (BRAVECTO Quantum™) against repeated infestations with Rhipicephalus sanguineus (sensu lato) and Ctenocephalides felis in dogs. Parasit Vectors. 2023;16(1):378. doi:10.1186/s13071-023-05989-6
- Fisara P, Guerino F. Year-round efficacy of a single treatment of fluralaner injectable suspension (BRAVECTO Quantum™) against repeated infestations with Ixodes holocyclus in dogs. Parasit Vectors. 2023;16(1):375. doi:10.1186/s13071-023-05986-9
- BRAVECTO® injectable (BRAVECTO 150 mg/mL powder and solvent for suspension for injection for dogs) [datasheet]. NOAH Compendium. Accessed August 1, 2025. https://www.noahcompendium.co.uk/?id=-485823&fromsearch=true#iosfirsthighlight
- BRAVECTO Dog Spot-On (fluralaner 280 mg/mL spot-on solution for dogs) [datasheet]. NOAH Compendium. Accessed August 1, 2025. https://www.noahcompendium.co.uk/?id=-461528&fromsearch=true#iosfirsthighlight
- BRAVECTO Plus Spot-on (fluralaner/moxidectin) [datasheet]. NOAH Compendium. Updated March 2023. Accessed August 1, 2025. https://www.noahcompendium.co.uk/?id=-469893&fromsearch=true#iosfirsthighlight
- BRAVECTO Cat Spot-on (fluralaner) [datasheet]. NOAH Compendium. Accessed August 1, 2025. https://www.noahcompendium.co.uk/?id=-481108&fromsearch=true#iosfirsthighlight
UK-BRV-240100002
Bravecto® Spot-on for Cats and Bravecto® Chewable Tablets, Spot-on for Dogs and Bravecto® 150 mg/ml powder and solvent for suspension for injection for dogs contain fluralaner. POM-V.
Bravecto® Plus Spot-on for Cats contains fluralaner and moxidectin. POM-V. Further information is available from the SPC, Datasheet or package leaflet.
Advice should be sought from the medicine prescriber. Prescription decisions are for the person issuing the prescription alone.
Use Medicines Responsibly.
MSD Animal Health UK Limited. Registered office Walton Manor, Walton, Milton Keynes MK7 7AJ, UK. Registered in England & Wales no. 946942.